Description
Component of a protein kinase signal transduction cascade (PubMed: 9808624). Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4 (PubMed: 9808624). May phosphorylate the MAPK8/JNK1 kinase (PubMed: 17761173). Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway (PubMed: 9808624)